The big picture in one paragraph

PFAS and microplastics are two different problems that share one strategy: stop the incoming load, then help the body clear what is already there. PFAS persist because the liver recycles them through bile — with serum half-lives of years — but clearance can be accelerated: regular blood or plasma donation (the strongest human evidence, ~30% PFOS reduction in a year), prescription bile-acid sequestrants that block recirculation (large declines in clinical studies), and gel-forming fiber with meals as a gentle daily habit. No supplement or herb has been shown to extract PFAS from cells. Microplastics, being solid particles, cannot be sweated out and have no proven clearance mechanism once embedded — so prevention (filtered water, no plastic in the microwave, glass storage, clean fish) is the primary lever, with a high-fiber diet speeding gut transit. And 'forever' is a nickname: engineered methods (SCWO, HALT, electrochemical, plasma, mechanochemical ball-milling, NaOH/DMSO) can actually cleave the C–F bond and destroy PFAS — the hard part is the scale of environmental dispersion, not the chemistry.